Paper prepared for the International Scientific Convention jointly organized by the Jordan
Society for Islamic Medical Studies, the Jordan Medical Association, and the Federation of Islamic Medical Associations at
Amman, Jordan 15-17 July 2004 by Professor Dr Omar Hasan Kasule, Sr. MB ChB (MUK), MPH & DrPH (Harvard), Deputy Dean for
Research and Postgraduate Affairs at the Faculty of Medicine, International Islamic University, Kuantan MALAYSIA E-MAIL email@example.com
Medical research is a form of ijtihad inspired by the teaching of the prophet that there is a cure for every
disease that must be searched for. The Islamic ethical theory on research is based on the 5 purposes of the Law, maqasid
al shari’at (religion, life, progeny, the mind, and wealth). If
any of the five is at risk permission is given to undertake human experiments that would otherwise be legally prohibited.
Therapeutic research fulfills the purpose of protecting health and life. Infertility research fulfils the purpose of protecting
progeny. Psychiatric research fulfills the purpose of protecting the mind. The search for cheaper treatments fulfills the
purpose of protecting wealth.
The 5 principles of the Law, qawa’id al shari’at, resolve
conflicts between and among the maqasid. Under the principle of intention,
qa’idat al qasd, research is judged by its underlying and not expressed intentions. Under the principle of
certainty, qa’idat al yaqeen, research on new treatment modalities is permitted if there are doubts about
existing modalities. Under the principle of injury, qa’idat al dharar, research is allowed if benefit
expected from the experimental therapy outweighs the potential risks. The principle of custom, qa’idat al
‘aadat, is used to define standards of good clinical practice (GCP) as what the majority of reasonable physicians
consider as reasonable.
Under the doctrine of istishaab,
an existing treatment is continued until there is evidence to the contrary. Under the doctrine of istihsaan a physician can ignore results of a new experiment
because of some inclination in his mind based on clinical intuition. Under the doctrine of istislaah medical research can be carried out in the public interest
although it causes inconvenience to individuals.
Informed consent by a legally competent research subject is mandatory for research. Informed consent is based on
the principle of intention. Of all the persons involved in research, the research subject who consents has the purest intentions
because he is at risk. Others involved in the research may have selfish motives that are not in the best interests of the
research subject. Informed consent does not legalize risky non-therapeutic research with no potential benefit. It is illegal
to force participation of the weak (prisoners, children, the ignorant, mentally incapacitated, and the poor) in research even
if they sign informed consent forms.
Findings of research should be widely disseminated either by teaching
or by publication for universal benefit. Islam enjoins dissemination of knowledge and prohibits hiding or monopolizing knowledge.
Islam puts emphasis on seeking knowledge[i]. It calls for benefiting from and using knowledge, al intifa’u
bi al ‘ilm wa al ‘amal bihi[ii]. There is no consideration for knowledge not accompanied by practical application, la ‘ilm bighayr ‘amal[iii].Islam also calls for tadabbur that is critical observation and consideration of information. The observation can be of the earth[iv]. Islam encourages active intellectual effort, ijtihad,
in looking for knowledge. The process of ijtihad is exertion of maximum intellectual
effort to discover the truth or understand the relation between truths. Ijtihad
is also used to discover and identify falsehoods. There are parallels between the tools of ijtihad used by classical Muslim scholars and the processes of reaching conclusions in empirical scientific research.
The process of inductive logic used in medical research is the same as qiyaas usuuli used by scholars of the methodology
of the Law, ulamaa usul al fiqh. The process of reaching a scientific consensus is similar to the process of scholarly
consensus, ijma al ‘ulama. Islam encourages search for cures, talab al dawaa. The prophet taught that
there is a cure for every disease, li kulli daai dawaa[v]. There is an injunction to search for cures by processes of medical research. Islam enjoins dissemination of knowledge[vi]. Dissemination of research findings by teaching or publication is encouraged. Islam
prohibits hiding knowledge, tahriim kitman al ‘ilm[vii].
2.0 HISTORICAL BACKGROUND
EARLY HUMAN EXPERIMENTS
Experiments on humans are as old as history. Early humans experimented with several plants and by trial and error
found some to be useful as medicines and others to be poisonous. Such trials have continued throughout human history giving
rise to a corpus of traditional medicine. Many medical systems including tibb nabawi represent empirical knowledge
accumulated over time by many informal and often un recognized medical experiments. These early experiments were not planned
in a systematic way neither were they documented.
Planned medical experiments are quite recent. Galen is credited with being the founder of experimental medicine
before 200M. In 1747M James Lind found out by experimentation that lemon juice prevented scurvy. Dr Edward Jenner found out
in 1798M that material from cowpox lesions prevented small pox. In 1914M Goldberger discovered the prevention of pellagra.
Experiments were sometimes carried out on whole communities such as the study of vitamin C in the prevention of the common
cold, the Salk vaccine trial, the HBV vaccine trials, the multiple risk factor intervention trial (MRFIT) against cardiac
disease, and fluoridation of community water supplies to prevent dental caries. Some trials were therapeutic such as the randomized
study of aspirin myocardial infarction study and the use of streptomycin in the treatment of tuberculosis (1948). Some studies
were preventive such as the women’s health study in which vitamin C and low dose aspirin were given to prevent cancer
and cardiovascular disease and the use of alpha-tocopherol and beta-carotene to prevent lung cancer among smokers.
Modern medicine would not have progressed as it has without some form of experimentation on humans. If a new drug
is to be used on humans, it has to be tried on humans because animal experiments are not adequate and may not be relevant
The search for new cures using human experimentation showed extreme forms of human transgression and disrespect
for human life in the Nazi inhumane medical experiments on prisoners in the Second European War (1939-1945M).
Despite the horror of the details revealed at the Nuremberg trials of Nazi medical experiments, unethical medical experiments
without informing the subjects or getting their consent continued after the war. In the 1950s M LSD and other drugs were used
in experiments to discover drugs that could control human behavior. In 1953M a CIA employee used in an experiment on LSD without
consent developed psychiatric symptoms and committed suicide. In 1953M Harold Blauer, a hospitalized psychiatric patient in
a research project funded by the US Army, died after injection of mescaline. In the period 1940s to 1960s M the US Atomic
Energy Commission conducted experiments on unsuspecting subjects including children to study the effect atomic weapon irradiation.
In 1954-56M elderly patients at the Brooklyn Jewish Chronic Diseases Hospital had cancer cells injected directly into their
veins. In the period 1932-1972M under the Tuskegee Syphilis Study, 400 Black American men with syphilis were deprived of any
treatment in a study of the natural history of syphilis without their informed consent. In 1946-1956 retarded teenage boys
in Massachusetts had radioactive iron and calcium put in their breakfast cereals.
In the early 1950s in Massachusetts pregnant women had radioactive iron injections
to study fetal circulation. Some of the pregnant women involved in the thalidomide disaster in the late 1950s were not informed
of the experimental nature of the drug.
2.0 EUROPEAN ETHICAL CODES
The Nuremberg code was laid down in 1946 in response to the criminal Nazi experiments on humans during the war. The World Medical
Association drew up the Helsinki Declaration, incorporating the Nuremberg
code, in 1964. The latest version (1996) was approved by The 48th Assembly of the World Medical Association held
in South Africa in 1996.
The Nuremberg and Helsinki
codes on experimentation have not been successful in stopping unethical research on subjects who are weak members of society.
As mentioned above, many unethical experiments were carried out in the US
soon after the Nuremberg code. The basic failure is that these codes lack a clear
identity. They are neither law that is enforceable using the normal legal procedures nor are they moral standards that are
enforced by the inner conscience of the experimenter. These codes are a reflection of the secularization of western society
in which morality was divorced from law and public affairs. Ethical codes are a bad attempt to mitigate the bad effects of
a divorce that should have never been allowed to occur in the first place.
Islam looks at problems of human experimentation as purely legal issues. The Law provides adequate guidelines and
safeguards. Islamic Law, unlike European law, incorporates morality in its fabric. There is therefore no need to have special
ethical codes outside the Law. The Islamic ethical guidelines for research are derived from the purposes of the Law, maqasid al shari’at, and the principles of the Law, qawa’id
2.0 PURPOSES OF THE LAW IN HUMAN EXPERIMENTATION
NECESSITIES, NEEDS, and REFINMENTS
Ethical issues of human experimentation can be discussed from the vantage point of the purposes of the law as set
out by the lawgiver. The purposes can be divided into three categories: necessities, dharuraat; needs, haajiyaat;
and refinements, tahsiinaat. Normal human life cannot exist and continue without dharuuraat. Haajiyat are for the proper functioning of life beyond the requirements of basic survival. They serve the purpose
of lifting difficulty, haraj, from people that would arise if the law provided
only for dharurat. Tahsinaat aim at achieving a higher level of human dignity. An example of a dharurat
is a life-saving drug like insulin for the insulin-dependent diabetic. An example of a haajat is a drug to treat mild
anxiety. An example of a tahsin is a cosmetic cream or female circumcision, al khafdh.
Human experimentation in order to fulfill dharuuraat has priority over
that research that aims at fulfilling haajiyaat. The Law will allow taking a higher risk for dharuuraat than
for haajiyaat. Experimentation for tahsiinaat may not be considered at all
if there is any risk.
PURPOSE OF PROTECTION OF RELIGION, hifdh al din
Experiments on humans become unethical when the scientists involved are not
guided by morality. Research on drugs and devices that will encourage immorality violates the purpose of protecting religion.
THE PURPOSE OF PROTECTION OF LIFE, hifdh al nafs
Experiments on humans for the purpose of finding new cures for disease fulfill
the purpose of protecting health and life. Often the benefit is general for the whole society and not for subjects of the
research. Phase 1 and phase 2 clinical trials may have no direct benefit to the patient but they provide basic scientific
information. Phase 3 trials have potential benefit for the patient. Phase 4 trials have a general societal benefit. The state
has a responsibility for the life and health of its citizens. It therefore must promulgate and enforce laws on the conduct
of human experiments in order to prevent abuses. It must be involved in the approval of drugs and devices for experiments
as well as ethical approval of protocols.
Death or other forms of injury consequent from an experiment trigger a
criminal charge of unintended manslaughter for which compensatory and not punitive damages are awarded, diyat. Informed
consent of the victim or his written statement relieving the physician or experimenter from liability is not admissible as
defense in this case. The strictness of the law on this matter is intended more for societal benefit to put those engaged
in experimentation on their toes so that mistakes are not made.
THE PURPOSE OF PROTECTION OF PROGENY, hifdh al nasl
Research on methods of curing infertility fulfils the purpose of protecting
progeny. The whole of medicine especially pediatrics and obstetrics also fulfils this purpose. Good health of potential parents
ensures that they will be healthy enough to bear the next generation. Good prenatal and obstetric care ensures delivery of
a healthy baby who therefore has more chances of growing into a healthy adult.
THE PURPOSE OF PROTECTION OF THE MIND, hifdh al ‘aql
Research on cure of mental conditions fulfills the purpose of protecting the mind. Research on other somatic diseases
fulfils the same purpose because any disease will through pain, suffering, and loss of function lead to mental symptoms of
depression and anxiety. Research on drugs and nutrients that alter the mind is justified in order to protect humans from such
THE PURPOSE OF PROTECTION OF WEALTH, hifdh al mal
In general good health ensures a healthy workforce that works to generate wealth for the community. Human experimentation
may lead to safer, more effective, and cheaper methods of treating disease which saves wealth.
3.0 PRINCIPLES OF THE LAW IN HUMAN EXPERIMENTATION
THE PRINCIPLE OF INTENTION, qaidat al maqsad
The basic principle is that each action is judged by the intention behind it, al umuur bi maqasidiha. A
research protocol is judged by the underlying objectives of the researcher as manifest in actual implementation and not the
stated objectives that may be deceptive. Means are judged with the same criteria as the intentions, al wasail laha hukm
al maqasid. If the intention, qasd, is wrong the means, wasiilah, is wrong and vice versa. Under this principle
a research protocol with beneficial scientific results will be rejected if the methods used are unethical.
THE PRINCIPLE OF CERTAINTY, qaidat al yaqeen
Human experimentation is carried out because of uncertainty about what is the best treatment. If there is certainty
that the current treatment is the best that there can be, an unlikely practical situation, then there is no legal justification
for further research. Further research cannot commence on the basis of some doubt about an existing treatment method. According
to the principle ‘certainty cannot be removed by doubt, al yaqeen la yazuulu bi al shakk’, there must be some empirical evidence of low efficacy in the current treatment or probable efficacy in the
new treatment before an experiment is authorized. Scientific conclusions are relative, probabilistic, and never 100% certain.
The Law recognizes the following descending order of gradation: certainty, yaqeen; predominant conjecture, ghalabat
al dhann; conjecture, al dhann; and doubt, al shakk.Yaqeen, is a situation when there is no doubt.
Dhann, is a situation in which there is some evidence in favor of one option but that evidence is not strong enough
to rule out the other alternatives. Shakk, is the opposite of yaqeen and is a situation in which there are two
or more competing options with no sufficient evidence to prove one of them as the most valid. Since yaqeen is unattainable
in science, we can make decisions based on ghalabat al dhann. In the absence of ghalabat al dhann, existing
treatments should continue in force until there is compelling evidence to change them, al asl baqau ma kaana ala ma kaana.
The above principles can protect against proliferation of human experiments that are unnecessary and are harmful but yet leave
room for those that have a good prospect of reaching a better treatment modality.
THE PRINCIPLE OF INJURY, qaidat al dharar
Human experimentation has associated potential hazards and risks. These risks have to be balanced against the injury
by disease and the potential benefit from the new treatment. The basic principle is that injury, if it occurs, should be relieved,
al dharar yuzaal. Thus a clinical trial in search of an effective cure for a disease is an attempt to remove an injury.
Preventive clinical trials are justified under the principle that an injury should be prevented as much as is possible, al
dharar yudfau bi qadr al imkaan. The new treatment being sought should not be as harmful as the disease condition according
to the principle that an injury is not relieved inflicting or causing an injury of the same degree, al dharar la yuzaal
bi mithlihi. Decisions to proceed with human experimentation involve a careful balancing of benefits and risks. The easiest
situation is when the potential benefit far outweighs the potential risk, in which case the research proceeds in pursuit of
the benefit. If the risk is equal to the benefit, we use the principle that prevention of a harm has priority over pursuit
of a benefit of equal worth, dariu an mafasid awla min jalbi al masaalih. If the risk is more than the benefit for
the individual research subject, but there is a larger societal benefit, we may proceed with the research under the principle
that public interest has priority over individual interest, al maslahat al aamat muqaddamat ala al maslahat al khaassat.
The individual may have to sustain a harm in order to protect public interest, yatahammalu al dharar al khaas li dafiu
al dharar al aam. In some situations benefits may not figure in the equation; the consideration being the injury of the
disease against the potential risk of the experiment. The principle of the law used is to choose the lesser of the two evils,
ikhtiyaar ahwan al sharrain.
PRINCIPLE OF HARDSHIP, qaidat al mashaqqat
Hardship mitigates easing of the sharia rules and obligations, al mashaqqa tajlibu al tayseer and necessity
legalizes the prohibited, al dharuraat tubiihu al mahdhuuraat. If any of the 5 necessities, al dharuraat al khamsat,
is at risk permission is given to undertake experiments that would otherwise be legally prohibited. Committing the otherwise
prohibited action should not extend beyond the limits needed to preserve the purpose of the law that is the basis for the
legalization, al dharuraat tuqaddar bi qadriha. Necessity however does not permanently abrogate the patient’s
right, al idhtiraar la yubtilu haqq al ghair. The law asserts vicarious liability. It is illegal to get out of a difficulty
by delegating to someone else to undertake a harmful act, ma haruma fi’iluhu, haruma talabuhu. Thus legal action
will be brought against all officials in the chain of command for negligence in experiments in their institution even if they
did not personally take part.
THE PRINCIPLE OF CUSTOM or PRECEDENT, qaidat al urf
The principle of custom is used to define standards of good clinical practice. The basic principle is that custom
or precedent has legal effect, al aadat muhakkamat. What is considered customary is what is uniform, widespread, and
predominant, innama tutabaru al aaadat idha atradat aw ghalabat, or is predominant, widespread, and not what is rare,
al ibrat li al ghaalib al shaiu la al naadir. Thus the standard of clinical care or experimental procedure is what
the majority of reasonable physicians consider as reasonable care and which constitutes a professional standard. An innovative
therapy is departure from the standard care. It is however allowed under the law but the physicians will be held liable for
any injuries to the patient. This liability also arises even if standard care were used. The Law recognizes that what is customary
changes with time, la yunkiru taghayyur al ahkaam bi taghayyuri al azmaan wa al ahwaal wa al aadaat wa a’raaf.
The doctrine of istishaab
is continuation of an existing ruling either affirming, ithbaat, or denying,
dafau. Matters are left as they are until there is evidence to the contrary. Recourse
is made to istishaab if there is no evidence, daliil.
This doctrine has the same impact as the principle of yaqeen discussed above.
The doctrine of istihsaan
is preference for one qiyaas over another because of evidence that the mujtahid feels more comfortable with or which is stronger. The evidence or reasoning may not be obvious, qiyaas khiffi. The doctrine operates in a clinical situation in which a physician obtains experimental evidence
about the efficacy of a new treatment but continues to use the old treatment because of some inclination in his mind. This
problem does not arise if Bayesian inference is used. The experimenter will have to state a probability of prior belief in
the efficacy of the new treatment. The results of the experiment are then used to generate a posterior probability from the
prior probability. The posterior probability may reinforce or decrease the original assumption. In this way prior clinical
experience or judgment is combined with new experimental evidence to reach a practical conclusion.
The doctrine of benefit, istislaah,
involves balancing benefits against potential harm. Istislah is obtaining
a benefit, jalb manufa'at, and preventing a harm, dafiu mafsadat. Preventing a harm has priority over obtaining a benefit, dafiu
al mafsadat muqaddamu ala jalb al maslahat. Human interest or benefit is the primary purpose of the law and is considered
in three types. Recognized benefits, maslahat mu'utabarat, are those related to
the 5 purposes of the law: ddiin, nafs, nasl, ‘aql, & maal. Considerations of most clinical trials fall under
recognized benefits. Abrogated benefits, maslahat mulghaat, are imaginary and are
not real for example planning a clinical trial of medication to change the appearance of normal males to females or drugs
to increase liver metabolism of alcohol and thus enable addicts to take more alcohol with delayed intoxication. Unclassified
benefits, maslahat mursalat, are those
for which the law did not mention any explicit text about their recognition or abrogation. Benefits of human experimentation
may be considered under maslahat mursalat following conditions laid down by the Malikis: conformity to the purposes
of the law, mulaimat li maqasid al shariat; being logical, ma'aquul; being necessary, dharuuri; serving public and not personal or private interest; and being real and not imaginary benefits.
Consideration of maslahat arises when we have to compare an existing to a new innovative treatment.
The potential benefit from the new treatment must be more than the standard treatment for the experiment to be allowed to
proceed. Consideration of maslahat also distinguishes a patient as a subject from
a healthy volunteer; the former may get some personal benefit from the experiment since experimentation is combined with care
whereas the latter has no benefits at all but may be exposed to hazards. Therapeutic research has immediate benefits whereas
the benefits of non-therapeutic research are remote. In non-therapeutic research, the subjects are volunteers who may be healthy
with or patients. In a randomized trial, subjects who receive a placebo have no benefit and no hazard but if they are patients
they are missing the potential benefits of either the traditional or the innovative treatment.
4.0 INFORMED CONSENT IN HUMAN EXPERIMENTATION
The commonest and most serious problem in human experiments is lack of proper informed consent. The
process of full disclosure that precedes patient consent usually creates enough transparency in the research process to prevent
fraud and malpractice. Consent to participation in an experiment does not void the duties and obligations of the traditional
doctor-patient relationship. Under the doctrine of sadd al dhari’at and in the interest of the public, the subject
cannot consent to relieve the physician from liability for negligent medical care or injury from the experimental procedures.
The Law acts on the basis that a person with full legal competence would not give consent if all the implications and hazards
of the experiment were explained to him or her does not recognize consent to an experiment with a clear preponderance of harm.
The Law recognizes the physician-patient relationship as a contract under which the patient expects reasonable care as well
as expressed or implied warranties and guarantees. In an experiment the research protocol is considered part of the contract
and any protocol violations are considered a breach of contract for which relief can be sought in a court of law under the
doctrine that Muslims are bound by the conditions of their agreement, al muslimuum ‘ala shurutihim.
Consent is allowed under the doctrine of the human temporary custody of life. Life belongs to Allah but a human
has temporary custody during his adult lifetime. It is wrong to argue that a human cannot make any decision to participate
in an experiment with potential hazard to life because he has no control over his life. He however is accountable for any
decisions made such as consenting to a highly risky experiment that has no potential benefits.
Consent is related to the fine balance between benefit and risk in an experiment. It is only the subject
of the experiment who has the most objective assessment of risks because his welfare is at stake. Others may have other interests
or pressures that color their judgment. The consent of a minor raises serious problems. The Law allows a guardian to make
decisions on behalf of the minor if they are clearly beneficial to the minor. The Law frowns on any decisions that may be
disadvantageous to the minor. Since a clinical trial has both benefits and hazards, the decision is very difficult to make.
A minor child with insight, mumayyiz, can be allowed to express his or her views but the final decision rests with
Consent can only be given by a person judged by the Law to be legally competent. Many experimental
subjects in en-ethical research are captive populations who cannot fulfill the conditions of legal competence. Hospitalized
patients may not feel free to refuse participation because they feel indebted or under the control of the physicians. Physicians
are looked at as authority figures expected not to do harm. Children and the mentally deficient may not have the intellectual
competence to evaluate the risks and benefits involved in an experiment in order to make an informed decision. Prisoners,
armed forces and police personnel, medical students may have undue pressure from superiors to consent to research that they
would normally refuse.
5.0 OUTSTANDING LEGAL ISSUES IN HUMAN EXPERIMENTS
NON THERAPEUTIC EXPERIMENTS
Non-therapeutic experiments have no direct or immediate benefit to the subject of the study but may
on the other hand expose him or her to hazards. These experiments are however necessary to generate scientific data on which
subsequent therapeutic trials can be based. Phase 1 and phase 2 clinical trials are non-therapeutic trials on terminal patients
who are not likely to benefit from the treatment. They however provide pharmacodynamic, pharmacokinetic, and efficacy data
used to design phase 3 studies.
Experiments in which whole communities and not individuals are inducted into an experiment such as
fluoridation of drinking water raises an important issue of informed consent. Many individuals either do not like to participate
or are not in a position to give informed consent
THERAPEUTIC CLINICAL TRIALS ON HUMANS
Therapeutic trials involve trials of new drugs, trials of new procedures, or trials of
new medical devices. Research subjects are either patients (terminal or recovery possible) or healthy volunteers (paid or
unpaid). The major ethical issues that arise are: forced participation of the weak (prisoners, children, the ignorant, mentally
incapacitated, and the poor), risk to life (short and long term), and lack of informed consent. The prophet forbade participating
in jihad without the blessings of the parents, la yaghzu illa bi ridha al waalidayn[viii]. Using the analogy of jihad, any person of whatever
age must seek the blessings of the parents before participation in a clinical trial. A wife can not participate in a clinical
trial without the husband’s permission.
RESEARCH ON HUMAN TISSUES
Human tissues used in research may be from living persons, dead bodies, or aborted fetuses.
The main ethical issue that arises is lack of proper informed consent and the possible increase in abortions for the sake
of obtaining fetal tissue for experimentation. A property and ethical issue may arise over ownership of cell lines and other
biological products developed from human tissues and patented for commercial use.
STUDY OF ANATOMY BY DISSECTION OF CADAVERS
Dissection of cadavers is very important for medical education. There
are really no alternatives to dissection. Cadavers may be abandoned persons or vagrants who have no relatives to bury them.
Cadavers may also be bought or donated. The main ethical issues that arise are: human dignity, Informed consent, and final
burial of all remains.
Post-mortem examination serves several purposes. It can be done for scientific research to understand the natural
history, complications, and treatment of a disease condition. It can be done for further education of physicians and medical
students especially when they compare their clinical diagnosis with the evidence from autopsy. The lessons learned will improve
their diagnostic and treatment skills in the future. Post mortems are also undertaken for forensic purposes to provide evidence
on the timing, manner, and cause of death. The ethical issues that arise are: removal of parts of the body, dignity of dead,
risk of disease spread, informed consent of the deceased or the family, and delay of burial.
Post mortem may be visualized as mutilation of the body that is forbidden. The human has dignity in both life and
death. Respect for the dead body is the guidance ogf the prophet to stand up when a funeral procession passes by, al qiyaam li al janaazat[ix]. It is dignity to be buried whole. Surgical operations on the body are an affront
to the dignity. The prophet forbade mutilation, nahyu al muthla[x]. Removal of some parts is looked at with disfavor. In cases in which a body is
buried without some of its parts, the parts when found later are washed, prayed for and buried in the same grave.
Post-mortem examination will lead to delay of burial when the sunnah is to bury as soon as possible. Delay of the
burial affects human dignity because of deteriorations in the body including a bad smell.
The balance of benefits and harms is difficult because intangibles like human dignity are involved. The benefit,
maslahat, of medical education against the harm of body mutilation, muthlat. Where foul play is suspected, a
post mortem examination becomes mandatory.
If a pregnant woman dies, attempts should be made to remove the fetus if it is alive and viable. If the fetus is
also dead, the issue is not clear. Removing the fetus is mutilation of the body for no clear purpose.
Use of human bodies in auto crass experiments is an affront to human dignity. It however provides valuable data
that is used in improved auto engineering for human safety.
Genetic experiments on human organisms, tissues, and cells give rise to many ethical problems. Transformed genes,
molecules, and even microorganisms may cause diseases hitherto unknown. They may lead to new forms of environmental pollution.
Drugs and surgical procedures that alter human behavior violate the purpose
of preservation of the mind, hifdh al ‘aql. Artificial alteration of the mind may be voluntary (medical, social,
perversion), or forced (abuse of prisoners and dissidents, experimentation on humans, criminal purposes).
There is basically no ethical problem
in scientific research on cell aging as well as epidemiological studies on risk factors of senescence. What matters is the
intention behind the research and to what use that research will be put. If the underlying intention is to prevent or delay
death, the research is not ethical. The life span is fixed for each individual and cannot be changed. If the intention of
the research is to understand the aging process so that preventive measures can be taken to maintain as high a quality of
life as possible, then such research is ethical and is acceptable. Present epidemiological and cell biological knowledge indicates
that many measures can be taken to control the aging process. Better nutrition (especially green vegetables and fruits), early
detection and treatment of disease, sheltering from cosmic radiation and other environmental exposures, can delay the aging
process. This does not however delay the ajal because any other competing cause
of death could operate.
Despite the best of efforts to police itself, the scientific research community still has cases of research fraud.
Fraud manifests as cooking or doctoring data, selective reporting of data, suppression of negative information, and ‘stealing’
others’ work. Financial gain, reputation, and the pressure to publish or perish are the driving forces behind fraud.